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Prostate Cancer
Treatment Guide™

Experts in Treating Prostate Cancer
Treatment
Description
Prostate Cancer
Patient Profile
Prostate Cancer
Treatments
Prostate Cancer
Survival Rates
Prostate Cancer
Side Effects
Therapy News View Procedures Share Your Experience

Hormone
Therapy

Prostate Hormone Therapy

Prostate hormone therapy suppresses, blocks, or eliminates testosterone to slow the tumor’s growth. Prostate Hormone
Therapy

Prostate hormone therapy suppresses, blocks, or eliminates testosterone to slow the tumor’s growth.

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Hormone Therapy Uses

Therapy can slow the tumor’s growth or lower a PSA level; it may be used before, during, or after other treatment. Hormone Therapy Uses

Therapy can slow the tumor’s growth or lower a PSA level; it may be used before, during, or after other treatment.

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Shrinking the Prostate

Surgical castration patients return home the day of the surgery. Treatment is given orally or by injection. Shrinking the Prostate

Surgical castration patients return home the day of the surgery. Treatment is given orally or by injection.

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Hormone
Therapy Effects

Hormone therapy does not destroy cancer but research has shown effectiveness in enhancing other treatments. Hormone
Therapy Effects

Hormone therapy does not destroy cancer but research has shown effectiveness in enhancing other treatments.

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Hormone Therapy
Side Effects

May cause impotence, weight gain, hot flashes, fatigue, loss of muscle mass; and hormone “flare” in LHRH use. Hormone Therapy
Side Effects

May cause impotence, weight gain, hot flashes, fatigue, loss of muscle mass; and hormone “flare” in LHRH use.

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Prostate News

Click here for the latest news on Hormone Therapy.Prostate News

Click here for the latest news on Hormone Therapy.

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Hormone Therapy
Videos

Click here to view Hormone Therapy procedures. Hormone Therapy
Videos

Click here to view Hormone Therapy procedures.

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Hormone Therapy
Experiences


Click here to share your Hormone Therapy experiences.Hormone Therapy
Experiences

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Brachytherapy

Chemotherapy

Cryotherapy & Cryosurgery

Radiation
Therapy

Prostatectomy

Robotic Prostatectomy

Watchful
Waiting

Complementary
and
Alternative Medicine

High Intensity
Focused
Ultrasound (HIFU)

Emerging Technologies

 

Results of Treating Prostate Cancer with Hormone Therapy and Prostatectomy

“Immediate Hormonal Therapy Compared with Observation After Radical Prostatectomy and Pelvic Lymphadenectomy in Men with Node-Positive Prostate Cancer”
Edward M. Messing, M.D., Judith Manola, M.S., Michael Sarosdy, M.D., George Wilding, M.D., E. David Crawford, M.D., and Donald Trump, M.D.

In this study 98 patients underwent radical prostatectomies and pelvic lymphadenectomies. All had nodal metastasis, or cancer spreading to the lymph nodes. At random, patients were assigned to receive immediate antiandrogen therapy following surgery. A doctor only observed the remaining patients. Physicians assessed patients quarterly during the first year and then semiannually. After 7 years, 7 of 47 patients who had received this therapy died, compared to 18 of 51 men in the observation group. Specifically, 3 men in the hormone group and 16 in the observation group died from prostate cancer. Those who were alive and had no evidence of recurrent disease consisted of 36 patients (77%) who had the hormones after their prostatectomy and 9 (18%) of patients who chose to observe their outcome after surgery.


“Neoadjuvant Hormone Therapy Before Salvage Radiotherapy for an Increasing Post-radical Prostatectomy Serum Prostate Specific Antigen Level”
TIGUERT, RABI; RIGAUD, JEROME; LACOMBE, LOUIS; LAVERDIERE, JACQUES; FRADET, YVES Journal of Urology. 170(2, Part 1):447-450, August 2003.

Within this study doctors retrospectively evaluated 81 patients who were treated with neoadjuvant androgen deprivation therapy before salvage external beam radiation treatment due to an increased PSA level following radical retropubic prostatectomy. Patients were analyzed based on the outcome of preoperative, pathological, postoperative characteristics, pre-salvage treatment, and radiation therapy. Prior to the salvage radiotherapy patients received a 3-month injection of a luteinizing hormone releasing hormone analogue. Doctors followed up with their patients approximately 38 months after external beam radiation and 91 months after radical prostatectomy. At 3 years 75% of patients were free of biochemical failure and 50% were at 5 years. Two patients (2%) died of prostate cancer. Those who benefited most from this treatment were patients with a pre-radiation PSA level less than 1 and a Gleason score less than 7.


“Incidence, Etiology, Location, Prevention, and Treatment of Positive Surgical Margins After Radical Prostatectomy for Prostate Cancer”
WIEDER, JEFF A.; SOLOWAY, MARK S. Journal of Urology. 160(2):299-315, August 1998.

In this study researchers reviewed recent literature regarding data on positive margins during radical prostatectomy. Artifacts induced by tissue processing, accidental incising into the prostate, and/or incising into extraprostatic tumor may all contribute to positive surgical margins. Those at higher risk of positive margins include patients with a PSA of 10 o greater, a Gleason score of 7, multiple positive biopsies, or stage T2b, T2c, or T3 cancer. Although neoadjuvant androgen deprivation does not delay progression or improve survival, it does reduce the incidence of positive margins.

 
 
 
 

 
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