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Among Patients Carrying BRCA Mutations, PARP Inhibitor Shows Activity In Pancreatic, Prostate Cancers
In the largest clinical trial to date to examine the efficacy of PARP inhibitor therapy in BRCA 1/2 carriers with diseases other than breast and ovarian cancer, the oral drug olaparib was found to be effective against advanced pancreatic and prostate cancers...
Advanced Prostate Cancer Drug Xofigo Approved By FDA
Xofigo (radium Ra 223 dichloride) has been approved by the US FDA for symptomatic late-stage (metastatic) castration-resistant prostate cancer that has reached bones but not other organs, i.e. with no known visceral metastatic disease. The Food and Drug Administration (FDA) approved Xifogo under the priority review program, three months ahead of schedule...
Comorbidities Taken Into Account Before Prostate Biopsy
UC Irvine Health urologists and health policy experts report in a new study that two written assessments that identify existing comorbidities - the patient-reported Total Illness Burden Index for Prostate Cancer (TIBI-Cap) and the physician-reported Charlson Comorbidity Index - can successfully target prostate patients who would not benefit from biopsy to discover possible cancer...
Exercise Lowers Risk Of Lung And Colorectal Cancer Among Middle Aged Men
New research conducted by researchers at the University of Vermont reveals that middle-aged men who engage in a lot of cardiovascular exercise are at a reduced risk of suffering from lung and colorectal cancer. In addition, those who exercise are less likely to die from prostate cancer (although their risk of contracting the disease remained the same)...
Androgen Deprivation Therapy For Prostate Cancer Can Cause Osteoporosis
Androgen deprivation therapy is a common and effective treatment for advanced prostate cancer. However, among other side-effects, it can cause significant bone thinning in men on long-term treatment...
Agent Orange Linked To Fatal Prostate Cancer
A new study of US Veterans has found that exposure to Agent Orange is linked to a two-fold higher risk of developing the most lethal forms of prostate cancer...
Agent Orange Exposure Linked To Life-Threatening Prostate Cancer
A new analysis has found a link between exposure to Agent Orange and lethal forms of prostate cancer among US Veterans. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the findings suggest that Agent Orange exposure history should be incorporated into prostate screening decisions for Veterans...
Prostate Cancer Tool Tested By UC San Francisco Helps Identify Those Best Suited For Active Surveillance
A new genomic test for prostate cancer can help predict whether men are more likely to harbor an aggressive form of the disease, according to a new UC San Francisco study. The test, which improves risk assessment when patients are first diagnosed, can also aid in determining which men are suitable for active surveillance - a way of managing the disease without direct treatment...
Soy And Tomato Combination May Help Prevent Prostate Cancer
Soy and tomato foods are probably better at preventing prostate cancer when eaten in combination than alone, researchers from the University of Illinois reported this week. John Erdman, professor of food science and nutrition, and colleagues used genetically engineered laboratory mice for their study. They were engineered to develop a fast-progressing aggressive form of prostate cancer...
Prostate Cancer Spread May Be Driven By Amplification Of A Stat5 Gene Which Produces Excess Oncogenic Protein
An international group of investigators, led by researchers at Thomas Jefferson University's Kimmel Cancer Center, have solved the mystery of why a substantial percentage of castrate-resistant metastatic prostate cancer cells contain abnormally high levels of the pro-growth protein Stat5...
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