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Prostate Cancer Treatment Guide

Treatment
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Prostate Cancer
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Prostate Cancer
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Prostate Cancer
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Cryosurgery &
Cryotherapy

Prostate Cryotherapy

Also called cryosurgery, this minimally invasive procedure uses needles to apply freezing gases to the prostate. Prostate Cryotherapy

Also called cryosurgery, this minimally invasive procedure uses needles to apply freezing gases to the prostate.

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Cryosurgery Patients

Cryosurgery is used for patients with localized cancer, external radiation recurrent cancer, Gleason scores under 6, or PSA levels under 10. Cryosurgery Patients

Cryosurgery is used for patients with localized cancer, external radiation recurrent cancer, Gleason scores under 6, or PSA levels under 10.

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Minimally Invasive Surgery

Cryosurgery takes about 2 hours with a possible overnight admission. Minimally Invasive
Surgery

Cryosurgery takes about 2 hours with a possible overnight admission.

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Cryosurgery
Survival Rates

Long-term clinical results are limited but promising. Cryosurgery
Survival Rates

Long-term clinical results are limited but promising.

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Cryosurgery
Side Effects

Side effects may include moderate pelvic pain, blood in urine, scrotal swelling, mild urinary urgency, and impotence. Cryosurgery
Side Effects

Side effects may include moderate pelvic pain, blood in urine, scrotal swelling, mild urinary urgency, and impotence.

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Prostate News

Click here for the latest news on Cryosurgery & Cryotherapy.Prostate News

Click here for the latest news on Cryosurgery & Cryotherapy.

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Cryosurgery &
Cryotherapy Videos

Click here to view Cryosurgery & Cryotherapy procedures. Cryosurgery &
Cryotherapy Videos

Click here to view Cryosurgery & Cryotherapy procedures.

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Cryosurgery &
Cryotherapy Experience


Click here to share your Cryosurgery & Cryotherapy experiences.Cryosurgery &
Cryotherapy Experience

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Brachytherapy

Chemotherapy

Hormone
Therapy

Radiation
Therapy

Prostatectomy

Robotic Prostatectomy

Watchful
Waiting

Complementary
and
Alternative Medicine

High Intensity
Focused
Ultrasound (HIFU)

Emerging Technologies

 

Prostate Cancer Information:
Cryotherapy Treatment

Also referred to as cryosurgery and cryoablation, prostate cryotherapy is a minimally invasive surgery capable of using controlled freeze and thaw cycles to destroy the disease.

Cryotherapy’s Role in the Treatment of Prostate Cancer
Because cryotherapy is relatively new, that is, lacking numerous long-term survival rate studies, cryotherapy is not used as often as radiation therapy for primary treatment. Cryotherapy, however, is effective in treating cases of prostate cancer that are radioresistant and recur as a result. Some doctors believe that the use of freezing temperatures rather than stronger doses of radiation therapy is more effective for radioresistant prostate cancer.

Prostate cryotherapy works because as cells freeze, ice crystals form inside and around them. The freezing and thawing processes destroy cells through dehydration, drastic changes in the pH levels, or prevention of the flow of red blood cells. Subjecting the prostate gland to freezing temperatures, specifically negative 40 degrees Celsius, also activates an anti-tumor response in the body. An anti-tumor response begins with the production of anti-bodies that work to eradicate the tumor.

The History of Cryotherapy
Cryoablation translates literally to “destruction of tissue by cold.” The concept of using sub-zero temperatures in the treatment of prostate cancer, especially on prostatic tissue that is radioresistant, has been around since the 19th century when mixtures of ice and salt were applied to the breast or cervix for the treatment of cancer. Modern cryotherapy began in 1966 with the use of liquid nitrogen. When cryotherapy was first used, the surgery was fully invasive. The first form of cryotherapy involved a perineal incision through which an instrument called the cryoprobe was placed. Liquid nitrogen was circulated through the probe to freeze the gland. In 1974, doctors began using a minimally invasive transperineal approach.

Today, 3rd generation cryotherapy needles are used more effectively through the guidance of the transrectal ultrasound. Only recently has the technology become available that allows a surgeon to carefully place and form an ice ball that will destroy the prostatic tissue. The technological advances include the switch from cryoprobes to cryoneedles, the use of the transrectal ultrasound for guidance, the switch from liquid nitrogen to argon and helium gases, and the use of a warming catheter.

Advantages and Disadvantages of Cryotherapy
Cryotherapy is an effective primary treatment for those who are in the early stages of prostate cancer with low risk for tumor extension. This treatment may also be an excellent alternative for those who are not good candidates for radical prostatectomy. Cryotherapy may be used if EBRT fails and the cancerous prostate cells are deemed radioresistant. Some advantages of include the one day in-hospital treatment, though some patients will stay overnight depending on their general health.

Cryotherapy can also be repeated if it fails to ablate the cancerous tissue during the first round of treatment. Patients for whom treatments fail can also pursue alternatives such as radiation therapy or prostatectomy. Because cryotherapy is minimally invasive, patients experience only minimal, if any, blood loss. One disadvantage is that the long-term data on cryotherapy is limited, due to its newness as mainstream prostate cancer treatment.

 
 
 

 
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