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Prostate Cancer Treatment Guide

Treatment
Description
Prostate Cancer
Patient Profile
Prostate Cancer
Treatments
Prostate Cancer
Survival Rates
Prostate Cancer
Side Effects
Therapy News View Procedures Share Your Experience

Radiation
Therapy

Prostate Radiation Therapy

EBRT or electron beam radiation therapy aims external radiation at prostate cancer cells. Prostate Radiation
Therapy

EBRT or electron beam radiation therapy aims external radiation at prostate cancer cells.

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Using Radiation Therapy

IMRT and 3D-CRT are newer versions of EBRT and are non-invasive. Using Radiation Therapy

IMRT and 3D-CRT are newer versions of EBRT and are non-invasive.

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Radiation Treatment

Radiation therapy generally requires 5 treatments per week over 6-8 weeks. Radiation Treatment

Radiation therapy generally requires 5 treatments per week over 6-8 weeks.

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External Radiation Outcomes

Multiple long- and short-term studies indicate success rates over 85% especially when used with other therapies. External Radiation
Outcomes

Multiple long- and short-term studies indicate success rates over 85% especially when used with other therapies.

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Radiation
Side Effects

May include tiredness, diarrhea, skin irritation, upset stomach, frequent or burning urination, and proctitis. Radiation
Side Effects

May include tiredness, diarrhea, skin irritation, upset stomach, frequent or burning urination, and proctitis.

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Prostate News

Click here for the latest news on Radiation Therapy.Prostate News

Click here for the latest news on Radiation Therapy.

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Radiation Therapy
Videos

Click here to view Radiation Therapy procedures. Radiation Therapy
Videos

Click here to view Radiation Therapy procedures.

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Radiation Therapy
Experiences


Click here to share your Radiation Therapy experiences.Radiation Therapy
Experiencse

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Brachytherapy

Chemotherapy

Cryotherapy & Cryosurgery

Hormone
Therapy

Prostatectomy

Robotic Prostatectomy

Watchful
Waiting

Complementary
and
Alternative Medicine

High Intensity
Focused
Ultrasound (HIFU)

Emerging Technologies

 

Results of Treating Prostate Cancer with Radiation Therapy and Hormone Therapy

“Optimizing Hormone Therapy in Localized Prostate Cancer: Focus on External Beam Radiotherapy”
SANDLER, HOWARD M. Journal of Urology. Innovations and Challenges in Prostate Cancer: Prevention, Detection and Treatment: Fourth International Conference. 172(5, Part 2 of 2) Supplement:S38-S41, November 2004.

The purpose of this study was to evaluate the use of hormone therapy when combined with radiotherapy prior to a radical prostatectomy. Physicians analyzed ongoing clinical trials in an effort to identify prostate cancer patients who will benefit most from this combination. In patients with low Gleason scores, short-term androgen ablation improved cause specific survival rates. For high-grade prostate cancer, long-term androgen ablation is required. Patients at intermediate risk are candidates for short-term androgen ablation, however there is a lack of trials that assess overall treatment benefit. Doctors advise patients with low risk prostate cancer to not receive androgen ablation unless additional data support a substantial clinical benefit. Patients with a high-risk for pelvic lymph node involvement may receive whole pelvic radiotherapy in order to maximize biochemical interaction.


“Hormonal Therapy and Radiotherapy for Localized Prostate Cancer: Who, Where, and How Long?”
ROACH, MACK III Journal of Urology. 170(6, Part 2 of 2):S35-S41, December 2003.

In this study 1, 323 patients with a risk of lymph node involvement greater than 15 percent were analyzed to determine the success rate of hormone therapy used with external beam radiation. Long-term hormone therapy was tested against short-term. Doctors compared whole pelvis radiotherapy, radiotherapy of the prostate alone, neoadjuvant hormone therapy and concurrent hormone therapy with radiotherapy, and radiotherapy with adjuvant hormone therapy. They strived to find out which one out of the four would most improve progression-free survival. After five years, all four treatments were contrasted and whole pelvis radiotherapy as well as neoadjuvant and concurrent hormone therapy with radiotherapy were found to be the best options in the improvement of progression-free survival.


“Neoadjuvant Hormone Therapy Before Salvage Radiotherapy for an Increasing Post-radical Prostatectomy Serum Prostate Specific Antigen Level”
TIGUERT, RABI; RIGAUD, JEROME; LACOMBE, LOUIS; LAVERDIERE, JACQUES; FRADET, YVES Journal of Urology. 170(2, Part 1):447-450, August 2003.

Within this study doctors retrospectively evaluated 81 patients who were treated with neoadjuvant androgen deprivation therapy before salvage external beam radiation treatment due to an increased PSA level following radical retropubic prostatectomy. Patients were analyzed based on the outcome of preoperative, pathological, postoperative characteristics, pre-salvage treatment, and radiation therapy. Prior to the salvage radiotherapy patients received a 3-month injection of a luteinizing hormone releasing hormone analogue. Doctors followed up with their patients approximately 38 months after external beam radiation and 91 months after radical prostatectomy. At three years 75% of patients were free of biochemical failure and 50% were at 5 years. Two patients (2 percent) died of prostate cancer. Those who benefited most from this treatment were patients with a pre-radiation PSA level less than 1 and a Gleason score less than 7.

 
 
 
 

 
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