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Prostate Cancer Treatment Guide

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Nortriptyline and Prostate Cancer Chemotherapy


Nortriptyline is in the class of drugs called tricyclic antidepressants. Nortriptyline treats depression by raising the level of neurotransmitters, such as serotonin and norepinephrine. In addition to treating depression, nortriptyline can be used to treat neuropathic pain which is caused by prostate cancer chemotherapy. Prostate cancer patients who must undergo chemotherapy may experience side effects of the nervous system that result in neuropathic pain. Neuropathic pain is difficult to treat; even the most powerful pain killers are usually ineffective. Researchers are not yet sure why tricyclic antidepressants have shown effectiveness in decreasing neuropathic pain; however, drugs like nortriptyline have been effective for neurological side effects of prostate cancer chemotherapy.

 
 
 

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