Estramustine Phosphate and Prostate Cancer Chemotherapy

Estramustine phosphate is a chemotherapy drug that is known as an alkylating agent and it used in the treatment of hormone-refractory prostate cancer and prostate cancer with bone metastasis. Estramustine phosphate works by binding the two strands of DNA that make up the double helix. The DNA cannot replicate, therefore the cell cannot divide.