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“Patterns of Positive Specimen Margins and Detectable Prostate Specific Antigen After Radical Perineal Prostatectomy”
Weldon V.E., Tavel F.R., Neuwirth H., and Cohen R.
During this study doctors analyzed
the prostate-specific
antigen levels of 200 patients who had undergone
radical
perineal prostatectomy. The patients all had prostate
cancer stages of T1 or T2 and had their prostatectomies
performed between 1984 and 1993. Radical perineal prostatectomy
in recent years has become a more popular prostate
cancer
treatment due to lower costs, shorter hospital stays,
and decreased morbidity. Radical perineal prostatectomy
has also become more popular due to the refinement of
the nerve-sparing technique that preserves sexual potency.
In 196 patients (18 laparoscopic cases) a concurrent bilateral
pelvic lymphadenectomy was performed. Throughout the
course of the study 8 planned prostatectomies were aborted
when lymphatic metastases was confirmed. Although all
patients underwent radical perineal prostatectomy, only
28 patients underwent a bilateral nerve sparing dissection.
One patient died of prostate cancer and two manifested
bone metastases during observation. After approximately
35 months, 79 percent of patients had undetectable PSA
levels. Researchers who examined the post-operative
pathologies of the two hundred patients’ prostate
glands found that 41 percent had experienced organ-confined
prostate cancer.
“Radical Perineal Prostatectomy in Obese Patients”
Boczko J., Melman A.
The objective of this study was to evaluate the effectiveness of radical perineal prostatectomy in obese patients. Drs. Boczko and Melman studied 103 patients who underwent radical perineal prostatectomies between 1996 and 2002. Of the 103 patients, doctors selected seven obese patients to participate in the study. To be eligible to participate patients had to have a body mass index greater than 30kg/m. The doctors then assessed the results of the patients’ prostate removals. The average age of the seven patients was 61 years, while the average body mass index was from 30.21 to 47.9. The average operation time lasted 142 minutes and 542mL of blood loss was reported. None of the seven patients experienced complications after their prostatectomies, and none of the seven required blood transfusions. After one year following the radical perineal prostatectomies, urinary continence rate reached 66%.
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