Stage M1 is a
component of the clinical staging for prostate cancer
established by the American Joint Committee on Cancer
(AJCC). In stage M1, distant metastasis of prostate
cancer has occurred. Stage M1 is further divided into
three subcategories denoted by the letters a, b, and
c. In stage M1a, the prostate cancer has metastasized
to nonregional lymph nodes, meaning not the nodes that
are adjacent to the bladder. In stage M1b, the prostate
cancer has metastasized to the bones. In stage M1c,
the prostate cancer has metastasized to other parts
of the body, either with or without extension to the
bones.
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